Candida Auris The Hidden Danger Threatening Global Health

Protection against Candida Auris with Doctor Silver Ion Products

To prevent the spread of Candida auris in hospitals
hygiene is of great importance. Doctor Silver Ion products play a critical role in surface and skin hygiene by showing a strong effect against Candida Auris and similar pathogens with the Silver Ion and Biopolymer Chitin it contains.
Disposable hygiene products developed especially for intensive care units, elderly care centers and home care patients.
products provide effective protection to minimize the risk of infection. Doctor Silver Ion formula,
penetrates the cell wall of microorganisms and inactivates pathogens.

A New Threat to Global Health: Candida Auris

Chief Physician of Eskisehir Osmangazi University Health Practice and Research Hospital Prof. Dr. Nurettin Erben
Nurettin Erben, in his article shared on Ekmud website, Candida Auris: For Global Health
He says there is a New Threat.

So what is this Candida Auris that is so dangerous that it is a Global Threat?

Candida Auris is a type of fungus that threatens human health. It is especially difficult to treat due to its multidrug resistance. Its resistance to fluconazole and amphotericin B, which are commonly used antifungal drugs, has caused it to become a problem that requires additional measures in the field of health. Some strains are also resistant to echinocandins, further limiting treatment options. The fact that it is difficult to diagnose and can be confused with other fungal species makes it easier for Candida Auris to cause hospital outbreaks.

Epidemiology and Spread

Candida was first isolated from an external ear drainage sample of a patient in Japan in 2009.
Auris, in retrospective investigations, was actually seen in South Korea in 1996.
understood. As of today, the United States, Canada, Colombia, India, Pakistan, Kuwait, Israel, South
It has been detected in many countries such as Africa, England, Germany, France, Spain. In Turkey
no cases have been reported to date. However, with increasing global mobility and healthcare
the failure to take special precautions against this pathogen will increase the likelihood of its occurrence in our country in the coming years.
increases the incidence of Candida Auris. The reasons for the simultaneous emergence of Candida Auris in different geographies are clear
is not known, but climate change, pesticides and the widespread use of antifungal drugs
such factors are thought to play a role.

Risk Factors

Candida Auris infections usually occur in patients with weakened immune systems. Most
common risk factors are:

• Long hospitalization
• Use of broad-spectrum antibiotics or antifungal drugs
• Use of central venous catheters, urinary catheters or tracheostomy tubes
• Diabetes or chronic renal failure
• Long-term treatment in intensive care units
• Patients undergoing cancer treatment and immunocompromised patients
  

The ability to survive on surfaces in hospitals for long periods of time is one of the main reasons why Candida Auris can cause outbreaks.
increases the risk.

Symptoms and Clinical Findings

Candida Auris infections usually occur in the bloodstream, surgical wound infections and ear
infections. More rarely, myocarditis, meningitis and bone
infections have also been reported. Serious outbreaks in patients treated in intensive care units
and is associated with high mortality rates. Candida Auris infection
It is reported that the mortality rate of patients with the disease ranges between 30% and 60%.

Diagnosis and the Problem of Misidentification

Accurate detection of Candida Auris by conventional laboratory methods is difficult. In many cases it is confused with Candida haemulonii, Candida famata or other candida species.
Advanced tests such as MALDI-TOF or PCR should therefore be used.

Treatment and the Problem of Resistance

Candida Auris has developed resistance to common antifungal drugs, making treatment options
limitations. Echinocandins are currently recognized as the most effective treatment, but
In some cases, resistance to these drugs may also develop. In patients who do not respond to treatment
liposomal amphotericin B may be used. CDC recommends antifungal treatment in patients without signs of infection.
that there is no need for treatment.

Prevention and Infection Control Measures

Precautions to be taken to prevent the spread of Candida Auris in the hospital environment are as follows:

• Paying utmost attention to hand hygiene
• Implementation of patient isolation
• Correct sterilization of medical equipment
• Preventing unnecessary use of antibiotics and antifungals
• Regular disinfection of hospital surfaces

Protection against Candida auris with Doctor Silver Ion Products

Ensuring hygiene is of great importance to prevent the spread of Candida Auris in hospitals. Doctor Silver Ion products play a critical role in surface and skin hygiene by showing a strong effect against Candida Auris and similar pathogens with the silver ion and biopolymer chitin it contains. Especially developed for intensive care units, elderly care centers and home care patients, disposable hygiene products are an effective way to minimize the risk of infection.
provides protection. The Doctor Silver Ion formula penetrates the cell wall of microorganisms and inactivates pathogens. In this way, the results against resistant pathogens such as Candida Auris
support measures.

Sources

• https://ekmud.org.tr/haber/201-son-zamanlarda-gundemde-olan-bir-etken-em-candida-auris-em
• Candida Auris. https://www.cdc.gov/fungal/candida-auris/index.html
• Dimitrios P Kontoyiannis. Worldwide epidemiology and the burden of Candida Auris. 13
  April 2019. ECCMID 2019 Amsterdam
• Jeffery-Smith A, Taori SK, Schelenz S, et al. Candida auris: a Review of the Literature. Clin
  Microbiol Rev. 2017;31(1):e00029-17.
• Cortegiani A, Misseri G, Fasciana T, Giammanco A, Giarratano A, Chowdhary A.
  Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida
  auris. J Intensive Care. 2018;6:69.
• Prof. Dr. Nurettin ERBEN, Eskisehir Osmangazi University Faculty of Medicine, Infection Diseases and Clinical Microbiology